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Tads Are 3D Structural Units Of Higher-Order Chromosome Organization In Drosophila


Tads Are 3D Structural Units Of Higher-Order Chromosome Organization In Drosophila. At a chromosome level, individual tads form contacts with other tads, preferentially of the same. These results indicate that tads are fundamental 3d genome units that engage.

CAVALLI Research Director Institute of Human (IGH
CAVALLI Research Director Institute of Human (IGH from www.researchgate.net

Domains (tads), which demarcate functional epigenetic domains defined by combinations of specific chromatin marks. However, whether tads are true physical units in each cell nucleus. Science advances, 4 (2) (2018), article eaar8082.

National Center For Biotechnology Information


However, whether tads are true physical units in each cell nucleus. At a chromosome level, individual tads form contacts with other tads, preferentially of the same. In drosophila, tads can be distinguished by the transcriptional state of the.

Scientific Article Published On 28 February 2018.


Cohesin is another prominent protein complex reported to be involved in 3d chromosome organization. A comprehensive analysis of the tridimensional (3d) organization of the genome is crucial to understand gene regulation. However, whether tads are true physical units in each cell nucleus or whether they reflect statistical frequencies of measured interactions within cell populations is unclear.

These Results Indicate That Tads Are Fundamental 3D Genome Units That Engage.


Science advances, 4 (2) (2018), article eaar8082. Domains (tads), which demarcate functional epigenetic domains defined by combinations of specific chromatin marks.


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